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33607002097452 | Adult Nonfiction | 618.85 HALPERN | Searching... Unknown | Searching... Unavailable |
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Summary
Summary
An essential behind-the-scenes foray into the world of cutting-edge memory research that unveils findings about memory loss only now available to general readers.
When Sue Halpern decided to emulate the first modern scientist of memory, Hermann Ebbinghaus, who experimented on himself, she had no idea that after a day of radioactive testing, her brain would become so "hot" that leaving through the front door of the lab would trigger the alarm. This was not the first time while researching Can't Remember What I Forgot , part of which appeared in The New Yorker , that Halpern had her head examined, nor would it be the last.
Halpern spent years in the company of the neuroscientists, pharmacologists, psychologists, nutritionists, and inventors who are hunting for the genes and molecules, the drugs and foods, the machines, the prosthetics, the behaviors and therapies that will stave off Alzheimer's and other forms of dementia and keep our minds--and memories--intact. Like many of us who have had a relative or friend succumb to memory loss, who are getting older, who are hearing statistics about our own chances of falling victim to dementia, who worry that each lapse of memory portends disease, Halpern wanted to find out what the experts really knew, what the bench scientists were working on, how close science is to a cure, to treatment, to accurate early diagnosis, and, of course, whether the crossword puzzles, sudokus, and ballroom dancing we've been told to take up can really keep us lucid or if they're just something to do before the inevitable overtakes us.
Beautifully written, sharply observed, and deeply informed, Can't Remember What I Forgot is a book full of vital information--and a solid dose of hope.
Author Notes
Sue Halpern is the author of "Migrations to Solitude". Her work has appeared in "Granta", "The New York Review of Books", "The New York Times", "Audubon", "Mother Jones", "Rolling Stone", & "Orion", among other publications. She lives in a small town in the Adirondack Mountains of New York.
(Bowker Author Biography)
Reviews (2)
Publisher's Weekly Review
Novelist and science writer Halpern (Four Wings and a Prayer) wades bravely into the morass of modern memory research to sort the truth from a wide assortment of "hyperbole and promises and platitudes." The news is mixed: most of us won't develop Alzheimer's, but everyone will suffer some memory loss. After describing the different types of memory, Halpern gamely undertakes a series of brain scans used to reveal brain damage and tries diagnostic tests that measure memory through the ability to recall words, images and smells. Researchers have identified a gene closely linked with Alzheimer's, but drugs to treat or prevent memory loss are still far from reality, Halpern says, adding that for many drug companies, the success of a remedy is measured only by how quickly it moves off the shelves. Armed with a mix of hope and healthy skepticism, the author also examines claims that eating chocolate (among other things) or solving puzzles can improve brain function. "So much of who we know ourselves to be comes from what we remember," Halpern writes, and her timely book offers a vivid, often amusing introduction to a science that touches us all. (May) (c) Copyright PWxyz, LLC. All rights reserved
Library Journal Review
Halpern's three-year inquiry into research on memory, aging, and Alzheimer's disease is an investigation of modern brain science rendered in creative nonfiction. Halpern gets to know a prominent neuroscientist, subjects herself to multiple tests (from paper-and-pencil tests to nuclear brain imaging), visits businesses involved in the quixotic race for memory-fixing drugs, and attends the Memory Olympics. She explains in plain English what science has discovered about learning and memory, what is currently agreed to improve memory, and what remains to be seen. No self-help book writer, Halpern has published four well-received books (e.g., Four Wings and a Prayer; Migrations to Solitude) and written for the New York Times, the New York Review of Books, and Slate magazine; she is frank and funny about her own fears and memory lapses and gently debunks memory-boosting fads, leaving the reader with few suggestions of what the ordinary person can do. Her book documents (with references) the great strides that have been made and holds out hope for real treatments for Alzheimer's and age-related memory loss. Educational, fabulously well written, and on a hot topic. Highly recommended for both public and academic libraries. [Halpern is married to nature writer Bill McKibben--Ed.]--Nancy Fontaine, Dartmouth Coll. Lib., Hanover, NH (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
Excerpts
Excerpts
Author's Note On the canted ceiling above my desk is a map of the brain. It shows the frontal lobe and temporal lobe and parietal lobe and occipital lobe as if they were places to visit-Rome, Milan, Trieste, San Remo. The map, of course, is dumb. It says nothing about what goes on in those places: that deep in the middle of the temporal lobe, which itself is deep in the middle of the brain, there is a tiny, cashew-shaped region called the hippocampus that is essential to forming new memories, or that the prefrontal cortex, which sits behind the eyebrows, is vital to foresight and being polite and paying attention, or that the occipital lobe, which brings up the rear of the brain, is central to sight itself. I look at that map sometimes and think about how it is my own brain apprehending it, and that to do so, it is traveling express. And then my mind, declaring its independence from my brain, begins to wander among the events of the day, past and future, and plans for summer vacation, and concern for a friend who is sick and the dog in the yard, but never getting so far afield that it doesn't heed its own call back. Near the map, tacked to the wall, is a picture of the brain that is doing all of that and all of this-this writing, thinking, typing, seeing-my brain, in bright colors, which was taken a few years ago in California. When I look at that picture I am not only seeing it, but recalling that day, or aspects of it, so much has gone out with the tide. I took notes on that trip, and carried a digital recorder, and have read and reread those notes over the years, and listened to the conversations, so I remember that day better than most, and what I remember comes with a certain confidence, but even so it is fuzzy. I cannot say, for instance, what kind of rental car I drove, or what book I was reading later that afternoon when I went to the beach, or which beach, specifically, it was. We rely on memory not only to remember, but to walk and dream and talk and smell and plan and fear and love and think and learn and more and more and more. Memory is how we know the world- that is a tree, this is a sentence-and know ourselves-I like chocolate ice cream, I am a singer-and know ourselves in the world. Amnesiacs make the case well: it is not, simply, that they don't remember their name or where they live, it is that absent memory, they are strangers to themselves. The English philosopher John Locke believed that we came into the world with our mind a blank slate, a "tabula rasa," ready for the pen of experience to inscribe. It's a perfect metaphor (even if it's not exactly true), because it works to describe what it's like to gain knowledge, and what it's like to lose your mind. Stroke by uneven stroke, the eraser plies the board. My father, before he died at the age of seventy-seven, had begun to know this intimately, though never to the extent that the board was wiped so clean that he approached Locke's natal state. He knew, and he talked about it-about how frustrating it was to read the newspaper and then have to read it again, or to stare at a can opener, not knowing what it was for, or to pick up the phone to call a friend, whose funeral he'd attended two years earlier. While it might have been natural for me to worry that my father's fate someday would be my own, I didn't, really. The doctor said he didn't have Alzheimer's disease, and since Alzheimer's disease tends to run in families, I figured I was safe. This was not one of those calculate-your-odds kind of conclusions. It wasn't a calculation at all. At best it was a passing thought. Call it denial, call it repression, or maybe arr Excerpted from Can't Remember What I Forgot: The Good News from the Front Lines of Memory Research by Sue Halpern All rights reserved by the original copyright owners. Excerpts are provided for display purposes only and may not be reproduced, reprinted or distributed without the written permission of the publisher.
Table of Contents
Author's Note | p. ix |
Chapter 1 Anxious | p. 1 |
Chapter 2 Certainty | p. 25 |
Chapter 3 Diagnosis | p. 50 |
Chapter 4 Normal | p. 78 |
Chapter 5 Inheritance | p. 101 |
Chapter 6 The Five-Year Plan | p. 129 |
Chapter 7 Gone to Mars | p. 152 |
Chapter 8 Signal to Noise | p. 181 |
Chapter 9 Input, Output | p. 206 |
Notes | p. 229 |
A Note on Sources | p. 239 |
Acknowledgments | p. 243 |
Index | p. 247 |